clinical trials

  • Department of Defense funds $8 million grant for Long COVID trials

    Department of Defense funds $8 million grant for Long COVID trials

    A new U.S. clinical trials program called PROBE-PASC was announced on Friday at a Long COVID conference in Amsterdam. The program received initial funding of $8 million from a Department of Defense (DOD) grant.

  • Research updates, September 1

    Research updates, September 1

    People with Long COVID are at a higher risk for cardiovascular, renal, and pulmonary (CRP) outcomes, according to a large observational study published in Journal of the American Heart Association. The study was a retrospective study and assessed more than 2.6 million people who developed COVID-19, comparing about 158,000 people who had been diagnosed with…

  • Research updates, August 25

    Research updates, August 25

    Another observational study found more evidence of endothelial dysfunction in Long COVID. German researchers evaluated the eyes of 102 people with Long COVID, comparing them to 102 people “recovered” from COVID-19, as well as controls.

  • Research updates, August 11

    Research updates, August 11

    COVID-19 can reactivate dormant viruses in the body, confirms new research in Nature.

  • Dysautonomia conference centers biomarkers and post-exertional malaise

    Dysautonomia conference centers biomarkers and post-exertional malaise

    The 14th annual Dysautonomia International conference outside Houston included presentations on the role of autoimmunity in dysautonomia and a biobank initiative for POTS research.

  • Research updates, July 28

    Research updates, July 28

    A new study found persistent neuromuscular abnormalities in Long COVID. The small follow-up study, published in Neurophysiologie Clinique, included 50 people with Long COVID who underwent two types of electromyography tests, which can provide objective measures of muscle function.

  • How to interpret clinical trial results for Long COVID

    How to interpret clinical trial results for Long COVID

    With no proven treatments or cures, many people with Long COVID are turning to off-label medications, supplements, and medical devices to treat their symptoms. There are numerous options — and some of them even have clinical trials underway or are reporting results. But even if one study suggests a treatment might work, another might contradict…

  • Research updates, July 21

    Research updates, July 21

    The dementia drug donepezil helped decrease fatigue in a subset of people with Long COVID, according to a study published in Frontiers in Pharmacology. In the complex study, which also included testing in mice, Japanese researchers found a majority of people with Long COVID in the cohort had reactivated human herpes virus 6 (HHV-6), which produced…

  • Experimental peptides are being advertised for Long COVID. But the evidence is trailing behind.

    Experimental peptides are being advertised for Long COVID. But the evidence is trailing behind.

    Some FDA-approved GLP-1s are being studied in clinical trials for the disease, but their results aren’t available yet. Experts caution against using experimental peptides for Long COVID.

  • Research updates, July 14

    Research updates, July 14

    COVID-19 can cause long-term eye disorders, according to a cross sectional study in Nature Communications. Researchers in Sweden assessed 100 people with Long COVID and compared them to 32 people who had COVID-19 and “recovered.”

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