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Research updates, October 29

Written by

Miles W. Griffis

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  • Long COVID may be a national security issue. A Lancet Regional Health: Americas study of nearly 900 United States Marines found that 25% developed Long COVID after their SARS-CoV-2 infections. Compared with a pre-pandemic cohort and an uninfected cohort, Long COVID had a “measurable” effect on the physical fitness of Marines. “The Marines affected with [Long COVID] showed evidence of long-term decrease in functional performance suggesting that SARS-CoV-2 infection may negatively affect health for a significant proportion of young adults,” the study’s authors wrote.
     
  • The National Institute of Allergy and Infectious Diseases (NIAID) is seeking feedback from people with Long COVID, researchers, and others following the RECOVER-Treating Long COVID meeting. They are seeking feedback on 1. Potential therapeutics for Long COVID; 2. Interest in being involved in working groups; 3. Biomarkers to be used in Long COVID clinical trials and finally; 4. General feedback on RECOVER-TLC. NIAID is collecting responses through February 1, 2025. You can submit a response here.
     
  • A new MedRxiv preprint found that 99.4% of Americans were estimated to have had at least one SARS-CoV-2 infection by the end of 2023.  The study’s authors stated that the continued evolution of the virus and waning immune protection led to a surge in cases in late 2023 because of the JN.1 variant. They wrote that the upturn “suggests that the U.S. population remains at risk of SARS-CoV-2 infection and severe COVID-19 disease despite the high level of cumulative exposure in the United States.”

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