- Researchers in China looked into the long-term molecular changes in people with Long COVID for a study published in BMC Medicine. They assessed 70 people who were hospitalized with COVID-19 during the first five months of the pandemic, and compared markers of their metabolism with pre-pandemic controls. They followed the participants for three years and found “concerning molecular sequelae” as well as suppressed immune responses.
- A new study in the Journal of Imaging assessed the eyes of people with neurological Long COVID symptoms and found potential retinal biomarkers. Researchers imaged the eyes of 30 people with Long COVID (who were not hospitalized) and compared them with 44 controls. They found that participants with Long COVID had significant changes to small blood vessels in the eyes. “The reduction in the retinal microvasculature…may serve as a biomarker for more diffuse small vessel disease in the brain that contributes to the cognitive dysfunction seen in Neuro-PASC patients,” the authors concluded. Watch one of the authors speak about the study in a short video on Contagion.
- A mixed-methods study in Rheumatology concluded what many with Long COVID already know: that psychosomatic and psychiatric misdiagnoses result in worse outcomes, including physical health and well-being. The study analyzed over 3,000 survey responses about systemic autoimmune rheumatic diseases (SARDs), as well as thorough in-depth interviews with over 100 clinicians and patients. “These types of misdiagnoses can create a multitude of negative feelings and impacts on lives, self-worth and care. These appear to rarely be resolved even after the correct diagnoses,” one of the authors said in a news release.
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