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Miles W. Griffis

  • Three clinical trials for Long COVID are testing JAK inhibitors to treat immune dysregulation

    Three clinical trials for Long COVID are testing JAK inhibitors to treat immune dysregulation

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    By

    Miles W. Griffis

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    Three separate trials are testing the immunomodulator drugs abrocitinib (Cibinqo), baricitinib (Olumiant), and upadacitinib (Rinvoq). All are JAK inhibitors, which target specific inflammation pathways.

  • Research updates, August 5

    Research updates, August 5

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    Miles W. Griffis

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    A drug originally developed for celiac disease was found to be safe and effective in treating a post-COVID syndrome in children, according to a new paper published in Science Translational Medicine.

  • Research updates, July 29

    Research updates, July 29

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    Miles W. Griffis

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    Two studies on potential biomarkers for myalgic encephalomyelitis (ME) were published this month. Plus, new studies about stellate ganglion blocks.

  • Research updates, July 22

    Research updates, July 22

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    Miles W. Griffis

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    A treatment for cats with a COVID-related infection may help advance Long COVID research. In a small study in Stem Cells Translation Medicine, researchers treated 10 cats who got feline infectious peritonitis (FIP), a feline coronavirus infection that triggers immune dysfunction, and found that those who received a combination of the antiviral drug GS-441524 and…

  • Research updates, July 15

    Research updates, July 15

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    Miles W. Griffis

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    A new study in PNAS found elevated oxidative stress was a shared characteristic in both myalgic encephalomyelitis (ME) and Long COVID.

  • Research updates, July 8

    Research updates, July 8

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    Miles W. Griffis

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    The biotech company Invivyd, which makes the COVID-19 monoclonal antibody Pemgarda, announced this week that it has launched the SPEAR Study Group to explore the drug for Long COVID and post-vaccine syndrome (PVS).

  • Research updates, July 1

    Research updates, July 1

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    Miles W. Griffis

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    Scientists found a new antiviral drug prototype that prevented Long COVID in mice and could also help treat the disease. In a study describing this milestone, published in Nature Communications, researchers stated the antiviral targets the coronavirus’ PLpro protein, as opposed to the Mpro protein, which Paxlovid targets.

  • Research updates, June 24

    Research updates, June 24

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    Miles W. Griffis

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    A new review paper published in Psychiatry and Clinical Neurosciences focuses on how Long COVID impacts the nervous and immune systems, and describes it as a neuroimmune condition.

  • Research updates, June 17

    Research updates, June 17

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    Miles W. Griffis

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    Pregnant people infected with SARS-CoV-2 during their first trimester were more likely to have smaller newborns, according to a new study in Pediatric Research.

  • Research updates, June 10

    Research updates, June 10

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    Miles W. Griffis

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    Three recent studies show the harmful effects of misdiagnosis for chronic diseases and conditions. The first, a meta-analysis in Psychological Bulletin of 151 studies encompassing 11 diseases (including Long COVID) and over 11,000 participants, found that medical gaslighting led to adverse impacts including diagnostic delay and emotional stress.

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