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The U.S. government is funding a $375 million effort for a new COVID-19 prevention drug for immunocompromised people, as part of Project NextGen. The federal health department provided the funds to the drug company Shionogi Inc. for a long-acting pre-exposure prophylactic (PreP) called S-892216 that blocks the main protease of SARS-CoV-2.


*Editor’s note: Julia Moore Vogel, an author of Paxlovid study, is on The Sick Times’ advisory board. Other authors are also affiliated with the Patient-Led Research Collaborative, which shares a funding source (the Balvi and Kanro funds) with The Sick Times. One author (JD Davids) is affiliated with Long COVID Justice, with which we collaborated…

A 2020 paper that spread controversial claims about the anti-malarial drug hydroxychloroquine as a treatment for COVID-19 was retracted last week. Published in the International Journal of Antimicrobial Agents, the paper was pulled for ethical concerns and other methodological problems. Earlier in the pandemic, the paper led to shortages of the drug for people with…

Editor’s note, December 19, 11am EST: The fourth summary has been updated to correct information about the patients who were autopsied. Related stories
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